Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat.

Genomics - 1 Dec 2006

Jagodic Maja, Olsson Tomas

Abstract excerpt

Unbiased genetic analysis of experimental autoimmune encephalomyelitis (EAE) can provide insights into the pathogenesis of multiple sclerosis. To date five genome-wide scans using F2 crosses between different inbred rats have been performed with the aim of defining EAE-regulating quantitative trait loci (QTLs) as the starting point for identification of the underlying genes. We here report the first...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Crosses, Genetic
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genome

Share to Quantitative Trait Loci

Share to Rats, Inbred Strains

Source

Identifiers

PMID: 17010567
DOI: 10.1016/j.ygeno.2006.08.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat.PMID 17010567Read ↗

Resolution of a 16.8-Mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyelitis quantitative trait loci and evidence for epistasis.Semantic proximity Read ↗

Identification of susceptibility genes for experimental autoimmune encephalomyelitis that overcome the effect of protective alleles at the eae2 locus.Semantic proximity Read ↗

An integrated genetic linkage map with 1,137 markers constructed from five F2 crosses of autoimmune disease-prone and -resistant inbred rat strains.Semantic proximity Read ↗

Fine-Mapping Resolves Eae23 into Two QTLs and Implicates ZEB1 as a Candidate Gene Regulating Experimental Neuroinflammation in RatSemantic proximity Read ↗

Analysis of CNS autoimmunity in genetically diverse mice reveals unique phenotypes and mechanisms.Semantic proximity Read ↗

Combining genetic mapping with genome-wide expression in experimental autoimmune encephalomyelitis highlights a gene network enriched for T cell functions and candidate genes regulating autoimmunity.Semantic proximity Read ↗

Multiple loci comprising immune-related genes regulate experimental neuroinflammation.Semantic proximity Read ↗

A genome-wide search identifies two susceptibility loci for experimental autoimmune encephalomyelitis on rat chromosomes 4 and 10.Semantic proximity Read ↗

Probing the basis of disease heterogeneity in multiple sclerosis using genetically diverse miceSemantic proximity Read ↗

Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research.Semantic proximity Read ↗

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.Semantic proximity Read ↗

IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.