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Article

Subsets of SNPs define rare genotype classes that predict ischemic heart disease.

Human genetics - 1 Feb 2007

Frikke-Schmidt Ruth, Sing Charles F, Nordestgaard Børge G, Steffensen Rolf, Tybjaerg-Hansen Anne

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are hypothesized to explain the genetic predisposition to ischemic heart disease (IHD) in the general population. Lack of evidence for a role of such variation is fostering pessimism about the utility of genetic information in the practice of medicine. In this study we determined the utility of exonic and 5' SNPs in apolipoprotein E (APOE) and lipoprotein lipase (LPL) when...

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Source

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Identifiers

PMID: 17006673
DOI: 10.1007/s00439-006-0233-y
PMCID: PMC1850964

Genes

LPL
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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