Article
An application of the patient rule-induction method for evaluating the contribution of the Apolipoprotein E and Lipoprotein Lipase genes to predicting ischemic heart disease.
Genetic epidemiology - 1 Sept 2007
Dyson Greg, Frikke-Schmidt Ruth, Nordestgaard Børge G, Tybjaerg-Hansen Anne, Sing Charles F
Abstract excerpt
Different combinations of genetic and environmental risk factors are known to contribute to the complex etiology of ischemic heart disease (IHD) in different subsets of individuals. We employed the Patient Rule-Induction Method (PRIM) to select the combination of risk factors and risk factor values that identified each of 16 mutually exclusive partitions of individuals having significantly different levels of...
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