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Article

Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis.

American journal of epidemiology - 1 Dec 2008

Sagoo Gurdeep S, Tatt Iain, Salanti Georgia, Butterworth Adam S, Sarwar Nadeem, van Maarle Merel, Jukema J Wouter, Wiman Björn, Kastelein John J P, Bennet Anna M, de Faire Ulf, Danesh John, Higgins Julian P T

Abstract excerpt

Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism and a major candidate gene for coronary heart disease (CHD). The authors assessed associations between 7 LPL polymorphisms and lipid fractions and CHD risk in population-based cohort, case-control, and cross-sectional studies published by January 2007. Meta-analyses of 22,734 CHD cases and 50,177 controls in 89 association studies focused on the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18922999
DOI: 10.1093/aje/kwn235

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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