Article
Altered intercellular communication in lung fibroblast cultures from patients with idiopathic pulmonary fibrosis
27 Sept 2006
Abstract excerpt
RATIONALE: Gap junctions are membrane channels formed by an array of connexins which links adjacent cells realizing an electro- metabolic synapse. Connexin-mediated communication is crucial in the regulation of cell growth, differentiation, and development. The activation and proliferation of phenotypically altered fibroblasts are central events in the pathogenesis of idiopathic pulmonary fibrosis. We sought to...
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