Article
Remodeling of cardiac fibroblasts following myocardial infarction results in increased gap junction intercellular communication.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000
Zhang Yan, Kanter Evelyn M, Yamada Kathryn A
Abstract excerpt
BACKGROUND: We have recently shown that native murine ventricular fibroblasts express both connexin43 (Cx43) and Cx45, and that the level of Cx43 expression influences intercellular coupling and cell proliferation. Relatively little is known, however, about how myocardial infarction (MI) influences expression of Cx43, or how altered Cx43 expression may affect fibroblast function post-MI. Fibroblasts are critical...
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