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Article

Connexin43 Controls the Myofibroblastic Differentiation of Bronchial Fibroblasts from Patients with Asthma.

American journal of respiratory cell and molecular biology - 1 Jul 2017

Paw Milena, Borek Izabela, Wnuk Dawid, Ryszawy Damian, Piwowarczyk Katarzyna, Kmiotek Katarzyna, Wójcik-Pszczoła Katarzyna A, Pierzchalska Małgorzata, Madeja Zbigniew, Sanak Marek, Błyszczuk Przemysław, Michalik Marta, Czyż Jarosław

Abstract excerpt

Pathologic accumulation of myofibroblasts in asthmatic bronchi is regulated by extrinsic stimuli and by the intrinsic susceptibility of bronchial fibroblasts to transforming growth factor-β (TGF-β). The specific function of gap junctions and connexins in this process has remained unknown. Here, we investigated the role of connexin43 (Cx43) in TGF-β-induced myofibroblastic differentiation of fibroblasts derived...

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Identifiers

PMID: 28245135
DOI: 10.1165/rcmb.2015-0255OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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