Article
Deletion of a single allele of Cx43 is associated with a reduction in the gap junctional intercellular communication and increased cell proliferation of mouse lung pneumocytes type II.
Cell proliferation - 1 Jun 2007
Avanzo J L, Mennecier G, Mesnil M, Hernandez-Blazquez F J, Fukumasu H, da Silva T C, Rao K V K, Dagli M L Z
Abstract excerpt
OBJECTIVES: Connexins (Cx) are proteins that form the gap junctional channels at neighbouring plasma membranes between adjacent cells. Cxs are involved in cell communication, which is reportedly correlated with cell proliferation and differentiation. Alterations in connexin expression and/or gap junctional intercellular communication (GJIC) capacity have long been postulated to be important in a number of...
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