Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Connexin43 is differentially distributed within renal vasculature and mediates profibrotic differentiation in medullary fibroblasts.

American journal of physiology. Renal physiology - 1 Jan 2021

Xu Yan, Hu Junda, Yilmaz Duygu Elif, Bachmann Sebastian

Abstract excerpt

Connexins (Cxs) form gap junctions for intercellular exchange of inorganic ions and messenger molecules. In the kidney, Cxs play essential roles within its compartments, but data on the precise cellular localization and cell type-related function of their isoforms are scarce. We tested whether Cx43 distribution is restricted to vascular and interstitial cells and whether medullary fibroblasts express Cx43 to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Communication
Share to Connexin 43

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Fibrosis

Share to Gap Junctions

Share to Kidney Medulla

Share to Myofibroblasts

Share to Rats, Wistar

Source

Identifiers

PMID: 33196322
DOI: 10.1152/ajprenal.00453.2020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Connexin43 is differentially distributed within renal vasculature and mediates profibrotic differentiation in medullary fibroblasts.PMID 33196322Read ↗

Activation of pericytesSemantic proximity Read ↗

Pericytes in kidney fibrosisSemantic proximity Read ↗

Gap Junctions or Hemichannel-Dependent and Independent Roles of Connexins in Fibrosis, Epithelial–Mesenchymal Transitions, and Wound HealingSemantic proximity Read ↗

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal TransitionSemantic proximity Read ↗

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney FibrosisSemantic proximity Read ↗

Connexins: Key Players in the Control of Vascular Plasticity and Function.Semantic proximity Read ↗

Reciprocal expression of connexin 40 and 45 during phenotypical changes in renin-secreting cells.Semantic proximity Read ↗

Connexin45 regulates endothelial-induced mesenchymal cell differentiation toward a mural cell phenotype.Semantic proximity Read ↗

Connexin43 Expression Levels Influence Intercellular Coupling and Cell Proliferation of Native Murine Cardiac FibroblastsSemantic proximity Read ↗

Renal fibrosis and the origin of the renal fibroblastSemantic proximity Read ↗

Origin and function of myofibroblasts in kidney fibrosisSemantic proximity Read ↗

Phenotypic modulation of renal cells during experimental and clinical renal scarring.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.