Article
Vasoactive intestinal peptide gene alterations in patients with idiopathic pulmonary arterial hypertension.
European journal of human genetics : EJHG - 1 Jan 2007
Haberl Ines, Frei Klemens, Ramsebner Reinhard, Doberer Daniel, Petkov Ventzislav, Albinni Sulaima, Lang Irene, Lucas Trevor, Mosgoeller Wilhelm
Abstract excerpt
Pulmonary arterial hypertension is a progressive disease, characterised by increased proliferation of pulmonary artery smooth muscle cells, vasoconstriction and remodelling of the vascular wall leading to right heart failure and death. The idiopathic form is rare (idiopathic arterial primary hypertension (IPAH); formerly PPH, MIM# 178600). Our group correlated a deficiency in vasoactive intestinal peptide (VIP;...
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