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Article

Vasoactive intestinal peptide gene polymorphisms, associated with its serum levels, predict treatment requirements in early rheumatoid arthritis.

Scientific reports - 1 Feb 2018

Seoane Iria V, Martínez Carmen, García-Vicuña Rosario, Ortiz Ana M, Juarranz Yasmina, Talayero Vanessa C, González-Álvaro Isidoro, Gomariz Rosa P, Lamana Amalia

Abstract excerpt

We previously reported that early arthritis (EA) patients with low vasoactive intestinal peptide (VIP) serum levels demonstrate a worse clinical disease course. In this study, we analysed whether variants in the VIP gene correlated with its serum levels and clinical EA parameters. The VIP gene was sequenced in patients with extremely high/low VIP levels, measured by enzyme immunoassay. Sixteen single nucleotide...

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Identifiers

PMID: 29391448
DOI: 10.1038/s41598-018-20400-6
PMCID: PMC5794878

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VIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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