Article
CD4+PD-1+ T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation.
Investigative ophthalmology & visual science - 1 Oct 2006
Meng Qianli, Yang Peizeng, Li Bing, Zhou Hongyan, Huang Xiangkun, Zhu Lianxiang, Ren Yalin, Kijlstra Aize
Abstract excerpt
PURPOSE: To study the expression and functional characteristics of programmed death-1 (PD-1) and its ligands in the spleens of mice undergoing anterior chamber-associated immune deviation (ACAID). METHODS: ACAID was induced in BALB/c mice by intracameral injection of ovalbumin (OVA). The expression of PD-1 and its ligands in the spleens of ACAID mice was determined by quantitative real-time PCR, Western blotting,...
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