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Article

Protective effects of agonistic anti-4-1BB antibody on the development of imiquimod-induced psoriasis-like dermatitis in mice.

Immunology letters - 1 Oct 2016

Yoo Jung Ki, Choo Young-Kug, Kwak Dong Hoon, Lee Jong Min, Lim Chi-Yeon, Lee Ju-Hee, Park Mi-Young, Kim Chang-Hyun

Abstract excerpt

Agonistic anti-4-1BB antibodies (Abs) play a central role in immunomodulatory conditions that control the pathogenesis of immune-mediated autoimmune and allergic diseases. However, the effects of agonistic anti-4-1BB Abs have not been examined in an experimental mouse model of psoriasis. Therefore, we investigated the protective effects of agonistic anti-4-1BB Abs, using imiquimod (IMQ)-induced psoriasis-like...

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Identifiers

PMID: 27592361
DOI: 10.1016/j.imlet.2016.08.012

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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