Article
Regulatory T cells in the actinic cheilitis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Nov 2014
Gasparoto Thaís Helena, de Souza Malaspina Tatiana Salles, Damante José Humberto, de Mello Edgard Franco, Ikoma Maura Rosane Valério, Garlet Gustavo Pompermaier, Costa Maria Renata Sales Nogueira, Cavassani Karen Angélica, da Silva João Santana, Campanelli Ana Paula
Abstract excerpt
BACKGROUND: Actinic cheilitis (AC) is an oral potentially malignant lesion which is the counterpart of actinic keratosis of the skin and has potential to develop into squamous cell carcinoma. Regulatory T cells (Tregs) have a critical role in modulating the antitumor immune responses. The presence of regulatory T cells in potentially malignant lesions has not been described. We chose investigate the involvement...
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