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Article

A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose

1 Oct 2006

Abstract excerpt

OBJECTIVES: A broad range of phenytoin doses is used in clinical practice, with the final 'maintenance' dose normally determined by trial and error. A common functional polymorphism in the SCN1A gene (one of the genes encoding the drug target) has been previously associated with maximum dose of phenytoin used clinically, and also maximum dose of carbamazepine, another antiepileptic drug with the same drug target....

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Identifiers

PMID: 17001291
DOI: 10.1097/01.fpc.0000230114.41828.73

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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