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Article

A functional polymorphism in the SCN1A gene is not associated with carbamazepine dosages in Austrian patients with epilepsy

1 Jun 2008

Abstract excerpt

To the Editors: The voltage gated sodium channel gene SCN1A can be regarded as a very attractive candidate gene for pharmacogenetic investigations in epilepsies. Work by the groups of Sisodiya and Goldstein has particularly implicated one functional polymorphism in this gene (IVS5N+5 G>A, rs3812718), which was suggested to influence the dosage requirements for the antiepileptic drugs carbamazepine and phenytoin...

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Identifiers

PMID: 18554361
DOI: 10.1111/j.1528-1167.2008.01549_4.x

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A functional polymorphism in the SCN1A gene is not associated with carbamazepine dosages in Austrian patients with epilepsyPMID 18554361Read ↗

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