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Article

Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs.

Molecular and cellular biology - 1 Dec 2006

Kostenko Elena V, Olabisi Oyenike O, Sahay Sutapa, Rodriguez Pedro L, Whitehead Ian P

Abstract excerpt

Dbs is a Rho-specific guanine nucleotide exchange factor (RhoGEF) with in vitro exchange activity specific for RhoA and Cdc42. Like many RhoGEF family members, the in vivo exchange activity of Dbs is restricted in a cell-specific manner. Here we report the characterization of a novel scaffold protein (designated cell cycle progression protein 1 [Ccpg1]) that interacts with Dbs and modulates its in vivo exchange...

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Identifiers

PMID: 17000758
DOI: 10.1128/MCB.00670-06
PMCID: PMC1636807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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