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Article

Generation of neutralization-resistant HIV-1 in vitro due to amino acid interchanges of third hypervariable env region.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 1990

Masuda T, Matsushita S, Kuroda M J, Kannagi M, Takatsuki K, Harada S

Abstract excerpt

Antigenic mutants of HIV-1 were isolated from three plaque-cloned viruses by the resistance of the virus to neutralizing mAb 0.5 beta against V3 domain of viral gp120, when the viruses were passaged in the presence of the antibody. However, when chronically infected MOLT-4 cells were treated with 0.5 beta mAb, recovered viruses from the 0.5 beta-treated cells showed no antigenic changes. The extent of genomic...

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Source

Identifiers

PMID: 1700002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Generation of neutralization-resistant HIV-1 in vitro due to amino acid interchanges of third hypervariable env region.PMID 1700002Read ↗

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