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Article

Genomic diversity and antigenic variation of HIV-1: links between pathogenesis, epidemiology and vaccine development.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 1991

Goudsmit J, Back N K, Nara P L

Abstract excerpt

Recent analysis of primate lentivirus genomes indicates that lentiviruses have infected primates for hundreds of years. The pathogenicity of such viruses may fluctuate due to the high evolution rate of some parts of the viral genome. Fixed nucleic acid substitutions in the gag gene appear to be caused by random fixation of selectively neutral mutants, whereas nonrandom fixation of selectively advantageous...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 2065891
DOI: 10.1096/fasebj.5.10.2065891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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