Article
Genotypic and phenotypic characterization of a neutralization-resistant breakthrough population of HIV-1.
Virology - 1 Apr 1996
Sirko D A, Ehrlich G D
Abstract excerpt
Certain antibody neutralization escape mutants of HIV-1 map outside of the antibody recognition epitope, thereby suggesting the presence of nonlinear conformational domains. In an effort to begin to define the interacting regions of the HIV envelope proteins, a neutralization-sensitive clone of H...
Topics
- Antibodies, Monoclonal
- Base Sequence
- Cell Line
- DNA, Viral
- Epitopes
- Genotype
- HIV Antibodies
- HIV Envelope Protein gp120
- HIV-1
- Humans
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Phenotype