Article
Genetic linkage and association studies in bipolar affective disorder: a time for optimism.
American journal of medical genetics. Part C, Seminars in medical genetics - 15 Nov 2003
Schulze Thomas G, McMahon Francis J
Abstract excerpt
Genetic research on complex diseases is beginning to bear fruit, with the successful identification of candidate susceptibility genes in diabetes, asthma, and other illnesses. Similar success is on the horizon for bipolar affective disorder (BPAD), but significant challenges remain. In this review, we outline the basic concepts of linkage and association mapping for complex phenotypes. We point out important...
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