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Article

A 6.9-Mb high-resolution BAC/PAC contig of human 4p15.3-p16.1, a candidate region for bipolar affective disorder.

Genomics - 1 Feb 2001

Evans K L, Le Hellard S, Morris S W, Lawson D, Whitton C, Semple C A, Fantes J A, Torrance H S, Malloy M P, Maule J C, Humphray S J, Ross M T, Bentley D R, Muir W J, Blackwood D H, Porteous D J

Abstract excerpt

Bipolar affective disorder (BPAD) is a complex disease with a significant genetic component and a population lifetime risk of 1%. Our previous work identified a region of human chromosome 4p that showed significant linkage to BPAD in a large pedigree. Here, we report the construction of an accurate, high-resolution physical map of 6.9 Mb of human chromosome 4p15.3-p16.1, which includes an 11-cM (5.8 Mb) critical...

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PMID: 11170748
DOI: 10.1006/geno.2000.6432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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