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Article

Peripheral myelin maintenance is a dynamic process requiring constant Krox20 expression.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Sept 2006

Decker Laurence, Desmarquet-Trin-Dinh Carole, Taillebourg Emmanuel, Ghislain Julien, Vallat Jean-Michel, Charnay Patrick

Abstract excerpt

Onset of myelination in Schwann cells is governed by several transcription factors, including Krox20/Egr2, and mutations affecting Krox20 result in various human hereditary peripheral neuropathies, including congenital hypomyelinating neuropathy (CHN) and Charcot-Marie-Tooth disease (CMT). Similar molecular information is not available on the process of myelin maintenance. We have generated conditional Krox20...

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Identifiers

PMID: 16988048
DOI: 10.1523/JNEUROSCI.0716-06.2006
PMCID: PMC6674452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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