Article
Endothelial nitric oxide synthase polymorphisms do not influence pulmonary artery systolic pressure at altitude.
High altitude medicine & biology - 1 Jan 2006
Smith Eve M D, Baillie J Kenneth, Thompson A A Roger, Irving John B, Porteous David, Webb David J
Abstract excerpt
Previous genetic association studies in high-risk subjects have suggested that polymorphisms in the gene encoding endothelial nitric oxide synthase (eNOS) may be associated with susceptibility to high altitude pulmonary edema (HAPE). We aimed to determine whether eNOS polymorphisms influence systolic pulmonary artery pressure measurements (PASP) in healthy trekkers ascending to high altitude. We examined two...
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