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Article

Bosentan reduces pulmonary artery pressure in high altitude residents.

High altitude medicine & biology - 1 Sept 2012

Kojonazarov Baktybek, Isakova Jainagul, Imanov Bakytbek, Sovkhozova Nurmira, Sooronbaev Talantbek, Ishizaki Takeshi, Aldashev Almaz A

Abstract excerpt

UNLABELLED: Endothelin-1 (ET-1) plays a critical role in the regulation of pulmonary vascular tone. The aim of this study was to investigate the role of ET-1 in the pathogenesis of high altitude pulmonary arterial hypertension (HAPH). METHODS: Pulmonary artery pressure (PAP) was measured by echoc...

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Source

Identifiers

PMID: 22994522
DOI: 10.1089/ham.2011.1107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22994522-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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