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Article

Association of moderate alpha-1 antitrypsin deficiency with lung cancer in the Serbian population.

Archives of medical research - 1 Oct 2006

Topic Aleksandra S, Jelic-Ivanovic Zorana D, Spasojevic-Kalimanovska Vesna V, Spasic Slavica M

Abstract excerpt

BACKGROUND: Alpha-1 antitrypsin (AAT) is an important serine protease inhibitor in human plasma. Its major physiological role is to inhibit neutrophil elastase (NE) in the lower respiratory tract and protect lung tissue from destruction. Recent studies indicated an etiological role of NE in lung cancer development. The aim of this study was to investigate the association of alpha-1 antitrypsin deficiency (AATD)...

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Identifiers

PMID: 16971227
DOI: 10.1016/j.arcmed.2006.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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