Article
Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes.
Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 2006
Tsutsumi Y, Jie X, Ihara K, Nomura A, Kanemitsu S, Takada H, Hara T
Abstract excerpt
AIMS: To investigate the contribution of regulatory T cells and co-stimulatory molecules in CD4(+) T cells to the development of Type 1 diabetes (T1D). METHODS: Twelve patients with T1D, nine patients with systemic lupus erythematosus (SLE), and 12 age-matched healthy control subjects participated. We analysed the proportions of CD25(+)CD4(+) T cells and natural killer T cells (NKT cells), and the expression...
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