CD1+ thymocytes proliferate and give rise to functional cells after stimulation with monoclonal antibodies recognizing CD3, CD2 or CD28 surface molecules.

doi:10.1016/0008-8749(90)90215-d

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Article

CD1+ thymocytes proliferate and give rise to functional cells after stimulation with monoclonal antibodies recognizing CD3, CD2 or CD28 surface molecules.

Cellular immunology - 1 Sept 1990

Zocchi M R, Marelli F, Poggi A

Abstract excerpt

The signal requirements for activation and proliferation of CD1+ thymocytes have been studied in order to define whether this immature cell population could function as mature T cells do. We found that CD1+ cells expressed high levels of CD25 antigen upon triggering with specific monoclonal antib...

Topics

Antibodies, Monoclonal
Antigens, CD
Antigens, CD1
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CD2 Antigens
CD28 Antigens
CD3 Complex
Cell Division
Child, Preschool
Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Infant

Lymphocyte Activation

Phenotype

Receptors, Antigen, T-Cell

Receptors, Immunologic

Receptors, Interleukin-2

Source

Open in PubMed

Identifiers

PMID: 1696526
DOI: 10.1016/0008-8749(90)90215-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1696526-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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