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Article

Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters.

Molecular and biochemical parasitology - 1 Nov 2000

LaCount D J, Bruse S, Hill K L, Donelson J E

Abstract excerpt

The discovery of double-stranded RNA interference (dsRNAi) in Trypanosoma brucei provides a convenient method to generate knockout phenotypes in this protozoan parasite [Ngo H, Tschudi C, Gull K, Ullu E. Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Proc Natl Acad Sci USA 1998;95:14687-14692]. The presence of double-stranded RNA (dsRNA) dominantly silences gene expression in a...

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PMID: 11087917
DOI: 10.1016/s0166-6851(00)00300-5

Genes

TUB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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