Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FeeM, an N-acyl amino acid synthase from an uncultured soil microbe: structure, mechanism, and acyl carrier protein binding.

Structure (London, England : 1993) - 1 Sept 2006

Van Wagoner Ryan M, Clardy Jon

Abstract excerpt

Attempts to access antibiotics by capturing biosynthetic genes and pathways directly from environmental DNA, which is overwhelmingly derived from uncultured bacteria, have revealed a large and previously unknown family of N-acyl amino acid synthases (NASs). The structure of the NAS FeeM reveals s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyl Carrier Protein
Share to Crystallography, X-Ray
Share to Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Molecular

Share to Protein Binding

Share to Protein Conformation

Share to Sequence Homology, Amino Acid

Share to Soil Microbiology

Source

Identifiers

PMID: 16962973
DOI: 10.1016/j.str.2006.07.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-16962973-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FeeM, an N-acyl amino acid synthase from an uncultured soil microbe: structure, mechanism, and acyl carrier protein binding.PMID 16962973Read ↗

Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic <i>Nocardia</i>Semantic proximity Read ↗

Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic NocardiaSemantic proximity Read ↗

Structural Comparison of Acinetobacter baumannii β-ketoacyl-acyl Carrier Protein Reductases in Fatty Acid and Aryl Polyene BiosynthesisSemantic proximity Read ↗

Characterization of Burkholderia pseudomallei protein BPSL1375 validates the Putative hemolytic activity of the COG3176 N-Acyltransferase family.Semantic proximity Read ↗

Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.Semantic proximity Read ↗

A universal pocket in fatty acyl-AMP ligases ensures redirection of fatty acid pool away from coenzyme A-based activation.Semantic proximity Read ↗

Efficient genetic code expansion tools enable <i>in vivo</i> study of lysine acetylation in non-model bacteriaSemantic proximity Read ↗

Wide variation in antibiotic resistance proteins identified by functional metagenomic screening of a soil DNA library.Semantic proximity Read ↗

Engineering dynamic gates in binding pocket of penicillin G acylase to selectively degrade bacterial signaling moleculesSemantic proximity Read ↗

Novel Rhizosphere Soil Alleles for the Enzyme 1-Aminocyclopropane-1-Carboxylate Deaminase Queried for Function with an In Vivo Competition Assay.Semantic proximity Read ↗

Lysobacter PilR, the Regulator of Type IV Pilus Synthesis, Controls Antifungal Antibiotic Production via a Cyclic di-GMP Pathway.Semantic proximity Read ↗

Unveiling the hidden biodiversity of microbial chemoreceptor genes in the rare biosphereSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.