Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wide variation in antibiotic resistance proteins identified by functional metagenomic screening of a soil DNA library.

Applied and environmental microbiology - 1 Mar 2012

McGarvey Kelly M, Queitsch Konstantin, Fields Stanley

Abstract excerpt

Most genes for antibiotic resistance present in soil microbes remain unexplored because most environmental microbes cannot be cultured. Only recently has the identification of these genes become feasible through the use of culture-independent methods. We screened a soil metagenomic DNA library in an Escherichia coli host for genes that can confer resistance to kanamycin, gentamicin, rifampin, trimethoprim,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to Drug Resistance, Bacterial

Share to Escherichia coli

Share to Gene Library

Share to Metagenome

Share to Soil Microbiology

Source

Open in PubMed Open full text

Identifiers

PMID: 22247132
DOI: 10.1128/AEM.06759-11
PMCID: PMC3298129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wide variation in antibiotic resistance proteins identified by functional metagenomic screening of a soil DNA library.PMID 22247132Read ↗

Integrative metagenomic and biochemical studies on rifamycin ADP-ribosyltransferases discovered in the sediment microbiome.Semantic proximity Read ↗

Uncultured soil bacteria are a reservoir of new antibiotic resistance genes.Semantic proximity Read ↗

Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT familySemantic proximity Read ↗

A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical LocationsSemantic proximity Read ↗

Functional screening of antibiotic resistance genes from human gut microbiota reveals a novel gene fusionSemantic proximity Read ↗

A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical LocationsSemantic proximity Read ↗

Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance GenesSemantic proximity Read ↗

A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteriaSemantic proximity Read ↗

Proteomics as the final step in the functional metagenomics study of antimicrobial resistanceSemantic proximity Read ↗

Suppression of antibiotic resistance evolution by single-gene deletion.Semantic proximity Read ↗

Functional metagenomic analysis reveals rivers are a reservoir for diverse antibiotic resistance genes.Semantic proximity Read ↗

Ecological context structures duplication and mobilization of antibiotic and metal resistance genes in bacteriaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.