Article
Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase.
BMC genomics - 8 Sept 2006
Brockmann-Gretza Olaf, Kalinowski Jörn
Abstract excerpt
BACKGROUND: The stringent response is the initial reaction of microorganisms to nutritional stress. During stringent response the small nucleotides (p)ppGpp act as global regulators and reprogram bacterial transcription. In this work, the genetic network controlled by the stringent response was characterized in the amino acid-producing Corynebacterium glutamicum. RESULTS: The transcriptome of a C. glutamicum rel...
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