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Article

Possible immunoregulatory role for CD5 + B cells.

Clinical immunology and immunopathology - 1 Aug 1990

Raveche E S

Abstract excerpt

CD5 + B cells represent a subpopulation of B cells which have the characteristic of employing unmutated immunoglobulin variable region genes. These cells are found to be increased early in ontogeny. The percentage of CD5 + B cells is highest in the fetus and decreases after birth. The antibodies produced by CD5 + B cells are polyreactive and are the natural autoantibodies. These autoantibodies may not be...

Topics

Animals
Antigens, Differentiation
Autoantibodies
Autoimmune Diseases
B-Lymphocytes
CD5 Antigens
Gene Rearrangement, B-Lymphocyte
Genes, Immunoglobulin
Humans
Mice
Mice, Inbred NZB
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1696187
DOI: 10.1016/0090-1229(90)90136-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1696187-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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