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Article

A critical role of lambda 5 protein in B cell development.

Cell - 29 May 1992

Kitamura D, Kudo A, Schaal S, Müller W, Melchers F, Rajewsky K

Abstract excerpt

The lambda 5 gene is a homolog of immunoglobulin J lambda-C lambda genes, expressed specifically in immature B-lineage cells. Lambda 5-encoded molecules form membrane complexes with mu or D mu proteins in association with an additional protein specifically expressed in immature B cells that is encoded by the Vpre-B gene. We have generated mice in which the lambda 5 gene is inactivated by targeted gene disruption...

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Identifiers

PMID: 1591779
DOI: 10.1016/0092-8674(92)90293-l

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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