Article
The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake.
Addiction biology - 1 Sept 2006
Quintanilla María E, Israel Yedy, Sapag Amalia, Tampier Lutske
Abstract excerpt
Ethanol non-drinker (UChA) and drinker (UChB) rat lines derived from an original Wistar colony have been selectively bred at the University of Chile for over 70 generations. Two main differences between these lines are clear. (1) Drinker rats display a markedly faster acute tolerance than non-drinker rats. In F2 UChA x UChB rats (in which all genes are 'shuffled'), a high acute tolerance of the offspring predicts...
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