Acetaldehyde metabolism: differences between UChA and UChB rats.

Abstract excerpt

In order to explore the influence of acetaldehyde (AcH) metabolism on the voluntary ethanol intake of genetically low (UChA) and high (UChB) ethanol consumer rats, the AcH disappearance rate (ADR) after incubation with homogenates and subcellular fractions from liver and brain was determined. In addition, the effect of disulfiram pretreatment on AcH metabolism was studied. Male adult rats of both strains were...

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