Warsaw high-preferring (WHP) and Warsaw low-preferring (WLP) lines of rats selectively bred for high and low voluntary ethanol intake: preliminary phenotypic characterization.

doi:10.1016/j.alcohol.2008.01.008

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Article

Warsaw high-preferring (WHP) and Warsaw low-preferring (WLP) lines of rats selectively bred for high and low voluntary ethanol intake: preliminary phenotypic characterization.

Alcohol (Fayetteville, N.Y.) - 1 May 2008

Dyr Wanda, Kostowski Wojciech

Abstract excerpt

The Warsaw High Preferring (WHP) and Warsaw Low Preferring (WLP) lines were bred from Wistar foundation stock to obtain lines of rats that differ in their preference for ethanol solutions. The WHP line has met several major criteria for an animal model of alcoholism. The WHP rats voluntarily drink excessive amounts of ethanol while the WLP rats consume negligible amounts of ethanol. The WHP rats attain...

Topics

Alcohol Drinking
Alcoholism
Animals
Body Weight
Brain Chemistry
Breeding
Central Nervous System Depressants
Conditioning, Operant
Dopamine
Eating
Ethanol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Male

Phenotype

Rats

Rats, Wistar

Sweetening Agents

Source

Open in PubMed

Identifiers

PMID: 18420111
DOI: 10.1016/j.alcohol.2008.01.008

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