Article
Relationship between neurokinin 2 receptor gene polymorphisms and serum vascular endothelial growth factor levels in patients with toluene diisocyanate-induced asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Sept 2006
Ye Y-M, Kang Y-M, Kim S-H, Kim C-W, Kim H-R, Hong C-S, Park C-S, Kim H-M, Nahm D-H, Park H-S
Abstract excerpt
BACKGROUND: Among the various pathogenic mechanisms of toluene diisocyanate (TDI)-induced asthma, a contribution from neurogenic inflammation has been suggested. OBJECTIVE: To evaluate neurokinin 2 receptor (NK2R) gene polymorphisms in association with the clinical phenotype of TDI-induced asthma, 70 TDI-induced occupational asthma (TDI-OA)patients, 59 asymptomatic exposed controls (AEC), and 93 unexposed healthy...
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