Article
Association between HLA genes and susceptibility to toluene diisocyanate-induced asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 2000
Mapp C E, Beghè B, Balboni A, Zamorani G, Padoan M, Jovine L, Baricordi O R, Fabbri L M
Abstract excerpt
BACKGROUND: Only a small proportion of subjects exposed to isocyanates develop occupational asthma, suggesting individual predisposition. The human leucocyte antigen (HLA) class II molecules may play a crucial role in the development of the immune response to isocyanates. OBJECTIVES: To investigate the role of HLA class II molecules in the development of toluene diisocyanate (TDI)-induced asthma. SUBJECTS:...
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