Article
Genomewide linkage screen for Waldenstrom macroglobulinemia susceptibility loci in high-risk families.
American journal of human genetics - 1 Oct 2006
McMaster Mary L, Goldin Lynn R, Bai Yan, Ter-Minassian Monica, Boehringer Stefan, Giambarresi Therese R, Vasquez Linda G, Tucker Margaret A
Abstract excerpt
Waldenstrom macroglobulinemia (WM), a distinctive subtype of non-Hodgkin lymphoma that features overproduction of immunoglobulin M (IgM), clearly has a familial component; however, no susceptibility genes have yet been identified. We performed a genomewide linkage analysis in 11 high-risk families with WM that were informative for linkage, for a total of 122 individuals with DNA samples, including 34 patients...
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