Article
Cytogenetics of familial Waldenstrom's macroglobulinemia: in pursuit of an understanding of genetic predisposition.
Clinical lymphoma - 1 Mar 2005
McMaster Mary L, Giambarresi Therese, Vasquez Linda, Goldstein Alisa M, Tucker Margaret A
Abstract excerpt
Despite recent identification of a recurrent chromosome 6q21 deletion in sporadic Waldenstrom's macroglobulinemia (WM), elucidation of the molecular pathogenesis of WM remains challenging. In contrast to the growing body of cytogenetic studies in sporadic WM, there have been virtually no informative studies of familial WM. The authors therefore undertook conventional and molecular cytogenetic evaluation of 18...
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