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Article

Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden.

American journal of human genetics - 1 Oct 2006

Roach Jared C, Deutsch Kerry, Li Sarah, Siegel Andrew F, Bekris Lynn M, Einhaus Derek C, Sheridan Colleen M, Glusman Gustavo, Hood Leroy, Lernmark Ake, Janer Marta

Abstract excerpt

We mapped the genetic influences for type 1 diabetes (T1D), using 2,360 single-nucleotide polymorphism (SNP) markers in the 4.4-Mb human major histocompatibility complex (MHC) locus and the adjacent 493 kb centromeric to the MHC, initially in a survey of 363 Swedish T1D cases and controls. We confirmed prior studies showing association with T1D in the MHC, most significantly near HLA-DR/DQ. In the region...

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Source

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Identifiers

PMID: 16960798
DOI: 10.1086/507876
PMCID: PMC1592562

Genes

ITPR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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