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Article

Promoter polymorphism of the anion-exchange protein 1 associated with severe malarial anemia and fatality.

The Journal of infectious diseases - 1 Oct 2006

von Kalckreuth Vera, Evans Jennifer A, Timmann Christian, Kuhn Daniela, Agbenyega Tsiri, Horstmann Rolf D, May Jürgen

Abstract excerpt

The anion-exchange protein 1 (AE1 or band 3) is involved in the erythrocyte invasion of the malaria parasite Plasmodium falciparum, the adhesion of infected erythrocytes to endothelial cells, and the regulation of acid-base homeostasis, which is a critical factor for human survival in severe malaria. A variant of the AE1 gene promoter 512 base pairs (bp) distant from the transcription start site and 5699 bp from...

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Identifiers

PMID: 16960783
DOI: 10.1086/507430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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