Article
HIV-2 Protease resistance defined in yeast cells.
Retrovirology - 6 Sept 2006
M'Barek Najoua Ben, Audoly Gilles, Raoult Didier, Gluschankof Pablo
Abstract excerpt
BACKGROUND: Inhibitors of the HIV-1 Protease currently used in therapeutic protocols, have been found to inhibit, although at higher concentrations, the HIV-2 encoded enzyme homologue. Similar to observations in HIV-1 infected individuals, therapeutic failure has also been observed for some patients infected with HIV-2 as a consequence of the emergence of viral strains resistant to the anti-retroviral molecules....
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