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Article

Surveyor nuclease-based genotyping of SNPs.

Clinical laboratory - 1 Jan 2006

Mitani Noriaki, Tanaka Shinobu, Okamoto Yasuyuki

Abstract excerpt

Surveyor nuclease, a single-strand-specific endonuclease that cleaves DNA at the 3' side of a base-mismatch site in both DNA strands, can be used for genotyping of SNPs by preparing two different types of a heteroduplex: one from mutant DNA fragments and the other from a mixture of wild-type and mutant fragments. We show an example of this technique and propose that it can be used with some advantages instead of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16955637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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