Article
Screening for mutations in kidney-related genes using SURVEYOR nuclease for cleavage at heteroduplex mismatches.
The Journal of molecular diagnostics : JMD - 1 Jul 2009
Voskarides Konstantinos, Deltas Constantinos
Abstract excerpt
SURVEYOR is a new mismatch-specific plant DNA endonuclease that is very efficient for mutation scanning in heteroduplex DNA. It is much faster, cheaper, more sensitive, and easier to perform than other "traditional" mutation detection methods such as single-strand conformation polymorphism analysis, denaturing high-performance liquid chromatography, heteroduplex analysis, and phage resolvases. This is the first...
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