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Article

Mutation detection using Surveyor nuclease.

BioTechniques - 1 Apr 2004

Qiu Peter, Shandilya Harini, D'Alessio James M, O'Connor Kevin, Durocher Jeffrey, Gerard Gary F

Abstract excerpt

We have developed a simple and flexible mutation detection technology for the discovery and mapping of both known and unknown mutations. This technology is based on a new mismatch-specific DNA endonuclease from celery, Surveyor nuclease, which is a member of the CEL nuclease family of plant DNA endonucleases. Surveyor nuclease cleaves with high specificity at the 3' side of any mismatch site in both DNA strands,...

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PMID: 15088388
DOI: 10.2144/04364PF01

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CEL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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