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Article

Genotyping with CRISPR-Cas-derived RNA-guided endonucleases.

Nature communications - 1 Jan 2014

Kim Jong Min, Kim Daesik, Kim Seokjoong, Kim Jin-Soo

Abstract excerpt

Restriction fragment length polymorphism (RFLP) analysis is one of the oldest, most convenient and least expensive methods of genotyping, but is limited by the availability of restriction endonuclease sites. Here we present a novel method of employing CRISPR/Cas-derived RNA-guided engineered nucleases (RGENs) in RFLP analysis. We prepare RGENs by complexing recombinant Cas9 protein derived from Streptococcus...

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Identifiers

PMID: 24445736
DOI: 10.1038/ncomms4157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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