Article
Expression of the Escherichia coli IrgA homolog adhesin is regulated by the ferric uptake regulation protein.
Microbial pathogenesis - 1 Dec 2006
Rashid Rebecca A, Tarr Phillip I, Moseley Steve L
Abstract excerpt
The IrgA homolog adhesin (Iha) is an adherence-conferring outer membrane protein of Escherichia coli associated with enterohemorrhagic and uropathogenic strains. Here, we used primer extension analysis to identify iha promoters in O157:H7 and uropathogenic E. coli strains. Transcriptional fusions demonstrated that iha transcription is repressed by iron. Gel shifts using purified ferric uptake regulator protein...
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