The ferric uptake regulator (Fur) homologue of Helicobacter pylori: functional analysis of the coding gene and controlled production of the recombinant protein in Escherichia coli.

doi:10.1007/s004300050102

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Article

The ferric uptake regulator (Fur) homologue of Helicobacter pylori: functional analysis of the coding gene and controlled production of the recombinant protein in Escherichia coli.

Medical microbiology and immunology - 1 Aug 1999

Bereswill S, Lichte F, Greiner S, Waidner B, Fassbinder F, Kist M

Abstract excerpt

A homologue of the ferric uptake regulator protein Fur has recently been identified within the Helicobacter pylori genome. The promoterless gene on a plasmid did partially complement a fur-negative mutant of Escherichia coli, and was strongly positive in the Fur titration assay (FURTA). The genetic and functional characterization of the complete fur homologue performed in this study revealed that the gene is...

Topics

Amino Acid Sequence
Bacterial Proteins
Blotting, Southern
Drug Resistance, Microbial
Escherichia coli
Gene Expression Regulation, Bacterial
Helicobacter pylori
Iron
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmids

Polymerase Chain Reaction

Recombinant Proteins

Repressor Proteins

Sequence Analysis, DNA

beta-Galactosidase

Source

Open in PubMed

Identifiers

PMID: 10691091
DOI: 10.1007/s004300050102

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